Gene
timp4.3
- ID
- ZDB-GENE-070824-1
- Name
- TIMP metallopeptidase inhibitor 4, tandem duplicate 3
- Symbol
- timp4.3 Nomenclature History
- Previous Names
-
- TIMP2d (1)
- timp4
- timp4a
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of proteolysis; response to cytokine; and response to hormone. Predicted to localize to extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR030490 | Tissue inhibitor of metalloproteinase, conserved site |
| Domain | IPR001134 | Netrin domain |
| Family | IPR001820 | Protease inhibitor I35 (TIMP) |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
| Homologous_superfamily | IPR027465 | Proteinase inhibitor I35b (TIMP), C-terminal |
Domain Details Per Protein
| Protein | Length | Netrin domain | Protease inhibitor I35 (TIMP) | Proteinase inhibitor I35b (TIMP), C-terminal | Tissue inhibitor of metalloproteinase, conserved site | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IT47
|
198 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timp4.3-201
(1)
|
Ensembl | 912 nt | ||
| mRNA |
timp4.3-203
(1)
|
Ensembl | 999 nt | ||
| ncRNA |
timp4.3-202
(1)
|
Ensembl | 656 nt |
Interactions and Pathways
No data available
Plasmids
No data available